The center

It was jointly created in 2008 by the French National Institute for Health and Medical Research (INSERM) [https://irmetist.labo.univ-poitiers.fr], the General Office of Healthcare Organization (DGOS), and the Poitiers University [https://www.univ-poitiers.fr].

In addition to clinical research, epidemiological approaches and human physiology explorations, the CIC developed technical innovation program in association with the PRISMATICS (Predictive Research In Spine Management/Neuromodulation And Thoracic Innovation In Cardiac Surgery) laboratory.

The CIC interface clinicians, scientists, and fundamental research teams particularly from INSERM, CNRS and universities. The CIC also contributes to the development of innovative and competitive research, the transfer of technology between academic and industry partners, the production of new scientific and medical knowledge, as well as training through research (PhD candidate from Rosalind Franklin doctoral school).

The CIC is located within Poitiers University Hospital (CHU Poitiers) site, close to the medical campus of the School of Medicine and Pharmacy [https://medphar.univ-poitiers.fr]- University of Poitiers.

The CIC is a member of the Institut Fédératif de Recherche (IFR) BioSanté (https://www.univ-poitiers.fr/decouvrir-la-recherche/equipes-de-recherche/les-laboratoires/institut-federatif-de-recherche-biosante/)

Coordinator

He has the general scientific responsibility for the activities implemented by the CIC. He organizes and manages the CIC’s medical activities at a strategic level.

Associate physician

He leads the daily activities of the CIC. He prepares the presentation of projects to the Technical Committee and nominates the reporters and any external experts. He also carries out medical consultations.

Associate pharmacist

She leads the daily activities of the CIC. She participates in the management of experimental health products stored at the CIC and linked with the University Hospital pharmacy.

Research nurse

She assists the investigators in the practical conduct of the study, ensures the usual or specialized investigative techniques and biological samples. She implements and monitors biomedical research techniques in cooperation with the investigators. She ensures the usual or specialized laboratory techniques, and packages and stocks samples. She may also manage patient visit schedules and organize their transport.

Biostatician

Apart from his own research, the biostatician provides methodological advice, and participates also in drafting protocols, in the analysis of results and publications.

Data manager

Is responsible for the design of electronic observation notebooks and is also responsible for management and data processing

Clinical Research Associate (CRA)

Ensures that the clinical trial runs smoothly from implementation to completion, while guaranteeing the quality of data and compliance with the regulations in effect (administrative and logistical procedures, compliance with GCP, data collection and patient’s follow- up). The CRA provides logistical support and assistance to the investigators.

Manager

Is responsible for administrative management of the CIC, organizing meetings and receiving investigators and industrials. The manager is also responsible for organizing meetings and preparing the activity reports of the center, and is the contact person for all issues.

Administrative secretary

Is responsible for the physical and telephonic reception of patients and collaborators of the CIC. Their goal is to help the whole team in drafting reports, research projects and medical reports for patients treated at the center.

Quality manager

Implements and maintains the CIC’s quality approach in line with changes in its activity and the regulatory texts in force. They participate in drafting and revising the CIC’s own procedures under the responsibility of the coordinating doctor, and are responsible for training staff in these procedures

Health executive

Is the interface between the departments of the University Hospital and the CIC. In collaboration with the coordinator, the health executive draws up and implements the general project of the CIC in line with institutional policy, and is also responsible for non-medical staff.

Biobank Research technician

Is responsible for the reception, preparation, storage and transfer of biological samples collections as part of the CIC’s biobank. Transfers are made in consultation with the research department of the University Hospital.

Research engineer

Is responsible for all aspects of the Biothèque’s biological sample preparation and conservation activities, in particular those relating to the cellulotheque. It facilitates the implementation of translational research programs in conjunction with the site’s fundamental research units.

Hospital services officer

The hospital services officer is responsible for cleaning the premises of the CIC, crockery, bedrooms, laundry and staff uniforms, as well as heating and serving meals for research subjects.

The Clinical Investigation Center (CIC) University Hospital of the Poitiers has set up a quality management system as described in the quality manual. The quality policy is supported by the department, which has signed a letter of commitment.
In 2024, the CIC aims to commit to the ISO-9001 v2015 certification process for its biomedical research activities.

Clinical Investigation

  •  Inclusion and follow-up of patients enrolled in clinical trials.
  •  Surveillance and monitoring of patients.

Biological Resource Center (CRB certified NF-96900)

Missions :

  •  Providing logistical and technical regulatory support to researchers for the creation and conservation of collections of human biological samples.
  •  Making human biological resources available to doctors and research teams as part of a research project.
  •  Structuring translational research between research units at the University Hospital, Inserm and the University of Poitiers.

Hypoxia chamber

Activities developed :

  •  Exploration of the effects of hypoxia on human metabolism
  •  The equipment incorporates a non-invasive vascular exploration chain, an ergo-cycle, non-invasive hemodynamic measurements and oxygenation parameters.

Neurophysiology platform

  •  Sleep exploration coupled with respiratory physiology measurements (non-invasive oxygenation, recording of diaphragm activity, electromagnetic phrenic stimulation, functional respiratory exploration).
  •  Evaluation of respiratory endurance after ventilatory stress or peripheral muscular exercise in patients and volunteers.

Interventional platform for public health « Vie La Santé »

Activities developed :

  •  Evaluation of the population health
  •  Pre-analytical platform for methods of estimating exposure to endocrine disruptors
  •  Biomonitoring and quantification of exposure biomarkers