{"id":8,"date":"2017-02-23T15:43:09","date_gmt":"2017-02-23T14:43:09","guid":{"rendered":"https:\/\/www.chu-poitiers.fr\/specialites\/plateforme-recherche-morphologique\/?page_id=8"},"modified":"2022-09-06T14:03:11","modified_gmt":"2022-09-06T12:03:11","slug":"tissue-micro-array-tma","status":"publish","type":"page","link":"https:\/\/www.chu-poitiers.fr\/specialites\/plateforme-recherche-morphologique\/tissue-micro-array-tma\/","title":{"rendered":"Tissue Micro-array (TMA)"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"zoom filet alignleft wp-image-126\" src=\"https:\/\/www.chu-poitiers.fr\/specialites\/plateforme-recherche-morphologique\/wp-content\/uploads\/sites\/62\/2017\/02\/station-motoris\u00e9e-TMABooste.jpg\" alt=\"station motoris\u00e9e TMABooster \" width=\"200\" height=\"133\" srcset=\"https:\/\/www.chu-poitiers.fr\/specialites\/plateforme-recherche-morphologique\/wp-content\/uploads\/sites\/62\/2017\/02\/station-motoris\u00e9e-TMABooste.jpg 600w, https:\/\/www.chu-poitiers.fr\/specialites\/plateforme-recherche-morphologique\/wp-content\/uploads\/sites\/62\/2017\/02\/station-motoris\u00e9e-TMABooste-300x200.jpg 300w\" sizes=\"auto, (max-width: 200px) 100vw, 200px\" \/><\/p>\n<p>Dot\u00e9e d\u2019une station motoris\u00e9e TMA<em>Booster <\/em>depuis 2005<em>, <\/em>la plateforme justifie d\u2019une longue exp\u00e9rience pour la fabrication, l\u2019analyse et l\u2019exploitation de TMA.<\/p>\n<p>Le principe du TMA est d\u2019inclure dans un bloc de paraffine plusieurs centaines de cylindres biopsiques pr\u00e9lev\u00e9s \u00e0 partir de diff\u00e9rents blocs et de pouvoir par la suite analyser ces \u00e9chantillons sur une seule lame.<\/p>\n<table>\n<tbody>\n<tr>\n<td><img loading=\"lazy\" decoding=\"async\" class=\"zoom filet wp-image-85 alignright\" src=\"https:\/\/www.chu-poitiers.fr\/specialites\/plateforme-recherche-morphologique\/wp-content\/uploads\/sites\/62\/2017\/02\/bloc-TMA.jpg\" width=\"255\" height=\"300\" srcset=\"https:\/\/www.chu-poitiers.fr\/specialites\/plateforme-recherche-morphologique\/wp-content\/uploads\/sites\/62\/2017\/02\/bloc-TMA.jpg 364w, https:\/\/www.chu-poitiers.fr\/specialites\/plateforme-recherche-morphologique\/wp-content\/uploads\/sites\/62\/2017\/02\/bloc-TMA-255x300.jpg 255w\" sizes=\"auto, (max-width: 255px) 100vw, 255px\" \/><\/td>\n<td><img loading=\"lazy\" decoding=\"async\" class=\"zoom filet wp-image-127 alignleft\" src=\"https:\/\/www.chu-poitiers.fr\/specialites\/plateforme-recherche-morphologique\/wp-content\/uploads\/sites\/62\/2017\/02\/bloc-TMA1.jpg\" width=\"450\" height=\"300\" srcset=\"https:\/\/www.chu-poitiers.fr\/specialites\/plateforme-recherche-morphologique\/wp-content\/uploads\/sites\/62\/2017\/02\/bloc-TMA1.jpg 600w, https:\/\/www.chu-poitiers.fr\/specialites\/plateforme-recherche-morphologique\/wp-content\/uploads\/sites\/62\/2017\/02\/bloc-TMA1-300x200.jpg 300w\" sizes=\"auto, (max-width: 450px) 100vw, 450px\" \/><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>Les blocs obtenus permettent la r\u00e9alisation de techniques compl\u00e9mentaires\u00a0: colorations sp\u00e9ciales, immuno-histochimie, FISH.<\/p>\n<p>L\u2019int\u00e9r\u00eat d\u2019une telle technique s\u2019explique par une consommation minime de tissus pour la constitution des TMA, et une homog\u00e9n\u00e9it\u00e9 des techniques compl\u00e9mentaires entre les diff\u00e9rents pr\u00e9l\u00e8vements.<\/p>\n<table>\n<tbody>\n<tr>\n<td><img loading=\"lazy\" decoding=\"async\" class=\"zoom filet wp-image-128 alignright\" src=\"https:\/\/www.chu-poitiers.fr\/specialites\/plateforme-recherche-morphologique\/wp-content\/uploads\/sites\/62\/2017\/02\/TMA-gros-plan.jpg\" width=\"375\" height=\"250\" srcset=\"https:\/\/www.chu-poitiers.fr\/specialites\/plateforme-recherche-morphologique\/wp-content\/uploads\/sites\/62\/2017\/02\/TMA-gros-plan.jpg 600w, https:\/\/www.chu-poitiers.fr\/specialites\/plateforme-recherche-morphologique\/wp-content\/uploads\/sites\/62\/2017\/02\/TMA-gros-plan-300x200.jpg 300w\" sizes=\"auto, (max-width: 375px) 100vw, 375px\" \/><\/td>\n<td><img loading=\"lazy\" decoding=\"async\" class=\"zoom filet wp-image-129 alignleft\" src=\"https:\/\/www.chu-poitiers.fr\/specialites\/plateforme-recherche-morphologique\/wp-content\/uploads\/sites\/62\/2017\/02\/TMA-points.jpg\" width=\"316\" height=\"250\" srcset=\"https:\/\/www.chu-poitiers.fr\/specialites\/plateforme-recherche-morphologique\/wp-content\/uploads\/sites\/62\/2017\/02\/TMA-points.jpg 398w, https:\/\/www.chu-poitiers.fr\/specialites\/plateforme-recherche-morphologique\/wp-content\/uploads\/sites\/62\/2017\/02\/TMA-points-300x237.jpg 300w\" sizes=\"auto, (max-width: 316px) 100vw, 316px\" \/><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>Cette technique permet de cribler de nombreux marqueurs sur d\u2019importantes s\u00e9ries de pr\u00e9l\u00e8vements, \u00e0 un moindre co\u00fbt.<\/p>\n<table>\n<tbody>\n<tr>\n<td><img loading=\"lazy\" decoding=\"async\" class=\"zoom filet wp-image-75 alignright\" src=\"https:\/\/www.chu-poitiers.fr\/specialites\/plateforme-recherche-morphologique\/wp-content\/uploads\/sites\/62\/2017\/02\/HES-TMA.jpg\" width=\"300\" height=\"206\" srcset=\"https:\/\/www.chu-poitiers.fr\/specialites\/plateforme-recherche-morphologique\/wp-content\/uploads\/sites\/62\/2017\/02\/HES-TMA.jpg 500w, https:\/\/www.chu-poitiers.fr\/specialites\/plateforme-recherche-morphologique\/wp-content\/uploads\/sites\/62\/2017\/02\/HES-TMA-300x206.jpg 300w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/td>\n<td><img loading=\"lazy\" decoding=\"async\" class=\"zoom filet wp-image-125 alignleft\" src=\"https:\/\/www.chu-poitiers.fr\/specialites\/plateforme-recherche-morphologique\/wp-content\/uploads\/sites\/62\/2017\/02\/station-de-num\u00e9risation.jpg\" width=\"300\" height=\"201\" srcset=\"https:\/\/www.chu-poitiers.fr\/specialites\/plateforme-recherche-morphologique\/wp-content\/uploads\/sites\/62\/2017\/02\/station-de-num\u00e9risation.jpg 600w, https:\/\/www.chu-poitiers.fr\/specialites\/plateforme-recherche-morphologique\/wp-content\/uploads\/sites\/62\/2017\/02\/station-de-num\u00e9risation-300x201.jpg 300w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>La plateforme dispose \u00e9galement d\u2019une station de num\u00e9risation (fond clair) d\u00e9di\u00e9e aux TMA permettant l\u2019obtention d\u2019une image spot par spot au grossissement X20.<\/p>\n<table>\n<tbody>\n<tr>\n<td><img loading=\"lazy\" decoding=\"async\" class=\"zoom filet aligncenter wp-image-130\" src=\"https:\/\/www.chu-poitiers.fr\/specialites\/plateforme-recherche-morphologique\/wp-content\/uploads\/sites\/62\/2017\/02\/grossissement.jpg\" width=\"375\" height=\"250\" srcset=\"https:\/\/www.chu-poitiers.fr\/specialites\/plateforme-recherche-morphologique\/wp-content\/uploads\/sites\/62\/2017\/02\/grossissement.jpg 600w, https:\/\/www.chu-poitiers.fr\/specialites\/plateforme-recherche-morphologique\/wp-content\/uploads\/sites\/62\/2017\/02\/grossissement-300x200.jpg 300w\" sizes=\"auto, (max-width: 375px) 100vw, 375px\" \/><\/td>\n<td><img loading=\"lazy\" decoding=\"async\" class=\"zoom filet wp-image-71 aligncenter\" src=\"https:\/\/www.chu-poitiers.fr\/specialites\/plateforme-recherche-morphologique\/wp-content\/uploads\/sites\/62\/2017\/02\/TMA-marron.jpg\" width=\"273\" height=\"250\" srcset=\"https:\/\/www.chu-poitiers.fr\/specialites\/plateforme-recherche-morphologique\/wp-content\/uploads\/sites\/62\/2017\/02\/TMA-marron.jpg 390w, https:\/\/www.chu-poitiers.fr\/specialites\/plateforme-recherche-morphologique\/wp-content\/uploads\/sites\/62\/2017\/02\/TMA-marron-300x275.jpg 300w\" sizes=\"auto, (max-width: 273px) 100vw, 273px\" \/><\/td>\n<td><img loading=\"lazy\" decoding=\"async\" class=\"zoom filet aligncenter wp-image-72\" src=\"https:\/\/www.chu-poitiers.fr\/specialites\/plateforme-recherche-morphologique\/wp-content\/uploads\/sites\/62\/2017\/02\/TMA-rose.jpg\" width=\"257\" height=\"250\" srcset=\"https:\/\/www.chu-poitiers.fr\/specialites\/plateforme-recherche-morphologique\/wp-content\/uploads\/sites\/62\/2017\/02\/TMA-rose.jpg 363w, https:\/\/www.chu-poitiers.fr\/specialites\/plateforme-recherche-morphologique\/wp-content\/uploads\/sites\/62\/2017\/02\/TMA-rose-300x292.jpg 300w\" sizes=\"auto, (max-width: 257px) 100vw, 257px\" \/><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><u><\/u><a href=\"https:\/\/www.chu-poitiers.fr\/specialites\/plateforme-recherche-morphologique\/contact\/\" target=\"_blank\" rel=\"noopener\">Nous contacter<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Dot\u00e9e d\u2019une station motoris\u00e9e TMABooster depuis 2005, la plateforme justifie d\u2019une longue exp\u00e9rience pour la fabrication, l\u2019analyse et l\u2019exploitation de TMA. Le principe du TMA est d\u2019inclure dans un bloc de paraffine plusieurs centaines de cylindres biopsiques pr\u00e9lev\u00e9s \u00e0 partir de diff\u00e9rents blocs et de pouvoir par la suite analyser ces \u00e9chantillons sur une seule [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-8","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Tissue Micro-array (TMA) - Plateforme de recherche morphologique<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.chu-poitiers.fr\/specialites\/plateforme-recherche-morphologique\/tissue-micro-array-tma\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Tissue Micro-array (TMA) - Plateforme de recherche morphologique\" \/>\n<meta property=\"og:description\" content=\"Dot\u00e9e d\u2019une station motoris\u00e9e TMABooster depuis 2005, la plateforme justifie d\u2019une longue exp\u00e9rience pour la fabrication, l\u2019analyse et l\u2019exploitation de TMA. Le principe du TMA est d\u2019inclure dans un bloc de paraffine plusieurs centaines de cylindres biopsiques pr\u00e9lev\u00e9s \u00e0 partir de diff\u00e9rents blocs et de pouvoir par la suite analyser ces \u00e9chantillons sur une seule [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.chu-poitiers.fr\/specialites\/plateforme-recherche-morphologique\/tissue-micro-array-tma\/\" \/>\n<meta property=\"og:site_name\" content=\"Plateforme de recherche morphologique\" \/>\n<meta property=\"article:modified_time\" content=\"2022-09-06T12:03:11+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.chu-poitiers.fr\/specialites\/plateforme-recherche-morphologique\/wp-content\/uploads\/sites\/62\/2017\/02\/bloc-TMA.jpg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.chu-poitiers.fr\\\/specialites\\\/plateforme-recherche-morphologique\\\/tissue-micro-array-tma\\\/\",\"url\":\"https:\\\/\\\/www.chu-poitiers.fr\\\/specialites\\\/plateforme-recherche-morphologique\\\/tissue-micro-array-tma\\\/\",\"name\":\"Tissue Micro-array (TMA) - 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