{"id":605,"date":"2026-08-25T09:44:19","date_gmt":"2026-08-25T08:44:19","guid":{"rendered":"https:\/\/www.chu-poitiers.fr\/specialites\/biologie-medicale\/?page_id=605"},"modified":"2026-08-25T10:37:50","modified_gmt":"2026-08-25T09:37:50","slug":"laboratoire-dimmunologie-et-inflammation","status":"publish","type":"page","link":"https:\/\/www.chu-poitiers.fr\/specialites\/biologie-medicale\/laboratoire-dimmunologie-et-inflammation\/","title":{"rendered":"Laboratoire d&rsquo;immunologie et inflammation"},"content":{"rendered":"<div class=\"wpb-content-wrapper\">[vc_row][vc_column][vc_row_inner][vc_column_inner width=\u00a0\u00bb1\/2&Prime;][vc_single_image image=\u00a0\u00bb611&Prime; img_size=\u00a0\u00bbfull\u00a0\u00bb alignment=\u00a0\u00bbcenter\u00a0\u00bb css=\u00a0\u00bb\u00a0\u00bb][\/vc_column_inner][vc_column_inner width=\u00a0\u00bb1\/2&Prime;][vc_single_image image=\u00a0\u00bb615&Prime; img_size=\u00a0\u00bbfull\u00a0\u00bb alignment=\u00a0\u00bbcenter\u00a0\u00bb css=\u00a0\u00bb\u00a0\u00bb][\/vc_column_inner][\/vc_row_inner][vc_row_inner][vc_column_inner width=\u00a0\u00bb1\/3&Prime;][vc_icon icon_fontawesome=\u00a0\u00bbfa fa-map-marker\u00a0\u00bb color=\u00a0\u00bbcustom\u00a0\u00bb align=\u00a0\u00bbcenter\u00a0\u00bb css=\u00a0\u00bb.vc_custom_1714122336260{margin-bottom: 5px !important;border-bottom-width: 0px !important;padding-bottom: 0px !important;}\u00a0\u00bb custom_color=\u00a0\u00bb#23b093&Prime;][vc_column_text]\n<p style=\"text-align: center;\">1<sup>er<\/sup> \u00e9tage du b\u00e2timent urgences et biologie m\u00e9dicale (UBM),<\/p>\n<p style=\"text-align: center;\">Site de la Mil\u00e9trie du CHU de Poitiers<\/p>\n[\/vc_column_text][\/vc_column_inner][vc_column_inner width=\u00a0\u00bb1\/3&Prime;][vc_icon icon_fontawesome=\u00a0\u00bbfa fa-phone\u00a0\u00bb color=\u00a0\u00bbcustom\u00a0\u00bb align=\u00a0\u00bbcenter\u00a0\u00bb css=\u00a0\u00bb.vc_custom_1714121889294{margin-bottom: 5px !important;border-bottom-width: 0px !important;padding-bottom: 0px !important;}\u00a0\u00bb custom_color=\u00a0\u00bb#ea5b0c\u00a0\u00bb][vc_column_text css=\u00a0\u00bb\u00a0\u00bb]\n<p style=\"text-align: center;\">05 49 44 37 46<\/p>\n[\/vc_column_text][\/vc_column_inner][vc_column_inner width=\u00a0\u00bb1\/3&Prime;][vc_icon icon_fontawesome=\u00a0\u00bbfa fa-users\u00a0\u00bb color=\u00a0\u00bbcustom\u00a0\u00bb align=\u00a0\u00bbcenter\u00a0\u00bb css=\u00a0\u00bb.vc_custom_1714122349228{margin-bottom: 5px !important;border-bottom-width: 0px !important;padding-bottom: 0px !important;}\u00a0\u00bb custom_color=\u00a0\u00bb#44b5e8&Prime;][vc_column_text css=\u00a0\u00bb\u00a0\u00bb]\n<p style=\"text-align: center;\"><strong>Chef de service\u00a0:<\/strong><br \/>\nPr Jean-Marc GOMBERT<\/p>\n<p style=\"text-align: center;\">Cadre de sant\u00e9 : Karline GUILLOTEAU<\/p>\n[\/vc_column_text][\/vc_column_inner][vc_column_inner][vc_column_text css=\u00a0\u00bb\u00a0\u00bb]Le service d\u2019immunologie et inflammation r\u00e9alise des techniques pour le diagnostic des patients ainsi que pour leur suivi.<\/p>\n<p>Le service r\u00e9alise environ 35 000 analyses\/an.<\/p>\n<p><strong>Secteur Inflammation\u00a0:<\/strong> L\u2019activit\u00e9 r\u00e9alis\u00e9e comprend des examens sp\u00e9cialis\u00e9s \u00e0 l\u2019interface Biochimie \/ Immunologie :<\/p>\n<ul>\n<li>d\u00e9pistage des immunoglobulines monoclonales ( \u00e9lectrophor\u00e8ses du s\u00e9rum, et de l\u2019urine), des bandes oligoclonales de la scl\u00e9rose en plaques (iso\u00e9lectrofocalisation du LCR), des h\u00e9moglobinopathies (\u00e9lectrophor\u00e8ses de l\u2019Hb)<\/li>\n<li>dosage pond\u00e9ral des prot\u00e9ines de l\u2019inflammation, immunoglobulines, explorations fonctionnelles du compl\u00e9ment, explorations de l\u2019allergie (IgE et m\u00e9diateurs)<\/li>\n<li>dosage de biomarqueurs de maladies neurod\u00e9g\u00e9n\u00e9ratives (LCR\u2026), de biomarqueurs cytokiniques de l\u2019inflammation, de syndromes lymphoprolif\u00e9ratifs\u2026(LCR, liquides oculaires, s\u00e9rum&#8230;)<\/li>\n<\/ul>\n<p><strong>Secteur Immunologie<\/strong>\u00a0: L\u2019activit\u00e9 porte principalement sur le diagnostic des maladies autoimmunes, des syndromes lymphoprolif\u00e9ratifs (my\u00e9lome, maladie de Waldenstr\u00f6m, leuc\u00e9mie lympho\u00efde chronique) ou de processus infectieux :<\/p>\n<ul>\n<li>identification des immunoglobulines monoclonales qui est n\u00e9cessaire au diagnostic et au suivi des syndromes lymphoprolif\u00e9ratifs\u00a0: dosage des chaines l\u00e9g\u00e8res libres s\u00e9riques, immunofixation s\u00e9rique et urinaire.<\/li>\n<li>la recherche et la d\u00e9termination de sp\u00e9cificit\u00e9s anticorps dans un certain nombre de maladies autoimmunes par immunofluorescence indirecte, ELISA, immunodot et chimiluminescence.<\/li>\n<li>tests d\u2019\u00e9valuation de la r\u00e9ponse cellulaire anti-infectieuse <em>in vitro<\/em>, par des tests \u00e9tudiant la production d\u2019IFN-g en r\u00e9ponse \u00e0 une stimulation par des antig\u00e8nes sp\u00e9cifiques (Mycobacterium tuberculosis, EBV, CMV, SARS-CoV2).<\/li>\n<li style=\"list-style-type: none;\"><\/li>\n<\/ul>\n[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_tta_accordion style=\u00a0\u00bbflat\u00a0\u00bb shape=\u00a0\u00bbsquare\u00a0\u00bb active_section=\u00a0\u00bb13&Prime; no_fill=\u00a0\u00bbtrue\u00a0\u00bb collapsible_all=\u00a0\u00bbtrue\u00a0\u00bb][vc_tta_section title=\u00a0\u00bbEquipe\u00a0\u00bb tab_id=\u00a0\u00bb1714122262188-068ff7d7-dd7e\u00a0\u00bb][vc_column_text css=\u00a0\u00bb\u00a0\u00bb]L\u2019\u00e9quipe m\u00e9dicale comprend 1 PU-PH, 1 MCU-PH, 1 AHU et 3 praticiens hospitaliers.<\/p>\n<p>Immunologie\u00a0:<\/p>\n<ul>\n<li>1 PU-PH, Pr Jean-Marc GOMBERT (Chef de service)<\/li>\n<li>1 MCU-PH, Dr Anne BARRA<\/li>\n<li>1 AHU, Dr Yasmine BADRI<\/li>\n<li>1 PH \u00e0 100 %, Dr Florence JACOMET<\/li>\n<\/ul>\n<p>Inflammation, allergie et cytokines\u00a0:<\/p>\n<ul>\n<li>1 PH \u00e0 100 %, Dr Anne BEAUME<\/li>\n<li>1 PH \u00e0 80 %, Dr Fabienne WITTHUHN<\/li>\n<\/ul>\n<p>L\u2019\u00e9quipe m\u00e9dico-technique est compos\u00e9e d&rsquo;un cadre de sant\u00e9 et de 6 techniciens de laboratoire.[\/vc_column_text][\/vc_tta_section][vc_tta_section title=\u00a0\u00bbSp\u00e9cificit\u00e9s\u00a0\u00bb tab_id=\u00a0\u00bb1714122262231-66899acf-ecda\u00a0\u00bb][vc_column_text css=\u00a0\u00bb\u00a0\u00bb]L\u2019activit\u00e9 de d\u00e9pistage des immunoglobulines monoclonales est associ\u00e9e \u00e0 celle du centre de r\u00e9f\u00e9rence maladie rare, maladie de d\u00e9p\u00f4ts (amylose, maladie de Randall, etc\u2026).[\/vc_column_text][\/vc_tta_section][vc_tta_section title=\u00a0\u00bbActivit\u00e9s de recherche\u00a0\u00bb tab_id=\u00a0\u00bb1714122270097-8a9e208d-bdc8&Prime;][vc_column_text css=\u00a0\u00bb\u00a0\u00bb]L\u2019activit\u00e9 de recherche du laboratoire est int\u00e9gr\u00e9e au sein de l\u2019UMR 1313 de l\u2019Inserm \u00ab Cellules souches leuc\u00e9miques et th\u00e9rapeutiques \u00bb. 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