{"id":73103503,"date":"2025-09-19T13:49:32","date_gmt":"2025-09-19T11:49:32","guid":{"rendered":"https:\/\/www.chu-poitiers.fr\/?p=73103503"},"modified":"2025-09-23T16:50:54","modified_gmt":"2025-09-23T14:50:54","slug":"la-bio-impression-3d-au-service-de-la-recherche-contre-le-cancer","status":"publish","type":"post","link":"https:\/\/www.chu-poitiers.fr\/en\/la-bio-impression-3d-au-service-de-la-recherche-contre-le-cancer\/","title":{"rendered":"La bio-impression 3D au service de la recherche contre le cancer"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">Fruit d\u2019un investissement conjoint entre le Canc\u00e9rop\u00f4le Grand Sud-Ouest, l\u2019Universit\u00e9 de Poitiers et le CHU de Poitiers, la plateforme OrgaPrint est d\u00e9sormais op\u00e9rationnelle gr\u00e2ce au recrutement de Maleaume Soulard, ing\u00e9nieur de recherche CHU dans l\u2019\u00e9quipe ProDiCeT, qui a jou\u00e9 un r\u00f4le d\u00e9terminant dans le d\u00e9veloppement de cette technologie.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Contrairement aux cultures cellulaires traditionnelles en 2D, qui restent limit\u00e9es pour mod\u00e9liser la complexit\u00e9 des tumeurs, la bio-impression permet de construire des structures en trois dimensions. Gr\u00e2ce \u00e0 des d\u00e9p\u00f4ts extr\u00eamement pr\u00e9cis de bio-encres compos\u00e9es de matrices, de cellules tumorales et d\u2019autres cellules du microenvironnement tumoral, il devient possible de cr\u00e9er des organo\u00efdes tumoraux.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">D\u2019un point de vue fondamental, ces mod\u00e8les reproduisent l\u2019h\u00e9t\u00e9rog\u00e9n\u00e9it\u00e9 et la complexit\u00e9 des cancers permettant aux chercheurs d\u2019observer les interactions entre les diff\u00e9rents types cellulaires aux cours de la progression tumorale. D\u2019un point de vue translationnel, l\u2019impression de dizaines de \u00ab&nbsp;mini-tumeurs&nbsp;\u00bb identiques permet de tester simultan\u00e9ment diff\u00e9rents traitements afin d\u2019identifier les mol\u00e9cules th\u00e9rapeutiques les plus efficaces. A terme, cela permettrait de combler le foss\u00e9 entre les \u00e9tudes pr\u00e9-clinique et les essais cliniques. Par ailleurs, l\u2019utilisation de la bioimpression 3D constitue une alternative \u00e9thique et pertinente \u00e0 l\u2019exp\u00e9rimentation animale.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Ax\u00e9e sur les tumeurs c\u00e9r\u00e9brales primitives et secondaires au sein de l\u2019\u00e9quipe ProDiCeT, la bio-impression introduit une dimension innovante dans la mani\u00e8re d\u2019aborder la recherche en oncologie. Pierre-Olivier Guichet et Maleaume Soulard ouvrent ainsi la voie \u00e0 une m\u00e9decine de demain plus cibl\u00e9e et plus efficace, o\u00f9 chaque patient pourrait b\u00e9n\u00e9ficier de mod\u00e8les tumoraux personnalis\u00e9s pour adapter son traitement.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><a href=\"https:\/\/www.chu-poitiers.fr\/wp-content\/uploads\/2025\/09\/BIO-IMPRIMANTE-7.jpg\"><img decoding=\"async\" width=\"900\" height=\"600\" src=\"https:\/\/www.chu-poitiers.fr\/wp-content\/uploads\/2025\/09\/BIO-IMPRIMANTE-7.jpg\" alt=\"\" class=\"wp-image-73103545\" srcset=\"https:\/\/www.chu-poitiers.fr\/wp-content\/uploads\/2025\/09\/BIO-IMPRIMANTE-7.jpg 900w, https:\/\/www.chu-poitiers.fr\/wp-content\/uploads\/2025\/09\/BIO-IMPRIMANTE-7-300x200.jpg 300w, https:\/\/www.chu-poitiers.fr\/wp-content\/uploads\/2025\/09\/BIO-IMPRIMANTE-7-768x512.jpg 768w, https:\/\/www.chu-poitiers.fr\/wp-content\/uploads\/2025\/09\/BIO-IMPRIMANTE-7-130x87.jpg 130w, https:\/\/www.chu-poitiers.fr\/wp-content\/uploads\/2025\/09\/BIO-IMPRIMANTE-7-550x367.jpg 550w\" sizes=\"(max-width: 900px) 100vw, 900px\" \/><\/a><\/figure>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>L\u2019\u00e9quipe ProDiCeT, dirig\u00e9e par le Pr Lucie Karayan-Tapon, franchit une \u00e9tape dans la recherche en oncologie en d\u00e9veloppant une technologie : la\u2026","protected":false},"author":12,"featured_media":73103539,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[96],"tags":[],"class_list":["post-73103503","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-non-classifiee"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>La bio-impression 3D au service de la recherche contre le cancer - Site du CHU de Poitiers<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.chu-poitiers.fr\/la-bio-impression-3d-au-service-de-la-recherche-contre-le-cancer\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"La bio-impression 3D au service de la recherche contre le cancer - Site du CHU de Poitiers\" \/>\n<meta property=\"og:description\" content=\"L\u2019\u00e9quipe ProDiCeT, dirig\u00e9e par le Pr Lucie Karayan-Tapon, franchit une \u00e9tape dans la recherche en oncologie en d\u00e9veloppant une technologie : la bio-impression 3D. Port\u00e9e par le Dr Pierre-Olivier Guichet, cette approche vise \u00e0 recr\u00e9er en laboratoire de v\u00e9ritables \u00ab avatars \u00bb de tumeurs, reproduisant fid\u00e8lement celles observ\u00e9es chez les patients. 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