{"id":5023,"date":"2015-01-29T11:46:40","date_gmt":"2015-01-29T10:46:40","guid":{"rendered":"http:\/\/chu-poitiers.ovh\/?p=5023"},"modified":"2015-09-16T14:32:47","modified_gmt":"2015-09-16T12:32:47","slug":"etude-clinique-le-service-de-reanimation-poursuit-ses-recherches-avec-succes","status":"publish","type":"post","link":"https:\/\/www.chu-poitiers.fr\/en\/etude-clinique-le-service-de-reanimation-poursuit-ses-recherches-avec-succes\/","title":{"rendered":"\u00c9tude clinique : le service de r\u00e9animation poursuit ses recherches avec succ\u00e8s"},"content":{"rendered":"

Lors de la pr\u00e9c\u00e9dente \u00e9tude dirig\u00e9e par le Dr Frat, intitul\u00e9e Florali 1 (high-flow oxygen therapy for the resuscitation of acute lung injury), trois m\u00e9thodes d\u2019oxyg\u00e9nation avaient \u00e9t\u00e9 observ\u00e9es pour diminuer le recours \u00e0 l\u2019intubation. Un panel de 52 patients avait particip\u00e9 \u00e0 ces recherches. Elles ont montr\u00e9 une baisse de la mortalit\u00e9 et des complications gr\u00e2ce \u00e0 l\u2019oxyg\u00e9noth\u00e9rapie nasale \u00e0 haut d\u00e9bit. Cette m\u00e9thode, d\u00e9velopp\u00e9e en Nouvelle-Z\u00e9lande il y a six ans, a aussi fait ses preuves au CHU de Montpellier. Elle consiste \u00e0 envoyer 70 litres d\u2019oxyg\u00e8ne humidifi\u00e9 et r\u00e9chauff\u00e9 par minute via des canules nasales, au lieu de 15 litres d\u2019oxyg\u00e8ne par minute via un masque. \u00ab Avec le Dr Arnaud Thille, nous sommes en train de r\u00e9diger les r\u00e9sultats de cette \u00e9tude, pr\u00e9cise le Dr Frat. Sa publication, dans le courant du mois de f\u00e9vrier, devrait rapidement avoir un impact sur la prise en charge des patients en r\u00e9animation. \u00bb<\/p>\n

L\u2019\u00e9tude Florali 2, qui d\u00e9butera probablement en septembre, sera d\u2019importance, puisqu\u2019elle concernera 320 patients r\u00e9partis dans 23 h\u00f4pitaux de France et de Belgique. Elle durera deux ans. Ce sera la premi\u00e8re \u00e9tude prospective, randomis\u00e9e et contr\u00f4l\u00e9e de cette ampleur dans le monde. Elle b\u00e9n\u00e9ficie du soutien de Reva (R\u00e9seau de recherche en ventilation artificielle), du Crics (Critical research in intensive care and sepsis), du CIC (centre de recherche clinique) via son module Alive et de la direction de la recherche clinique et de l\u2019innovation du CHU.<\/p>\n","protected":false},"excerpt":{"rendered":"

Le Dr Jean-Pierre Frat, praticien hospitalier en r\u00e9animation m\u00e9dicale, vient d\u2019obtenir le financement (395 000 euros) de sa future \u00e9tude via un\u2026","protected":false},"author":1,"featured_media":5025,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[53,41,1],"tags":[],"class_list":["post-5023","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-anesthesie","category-recherche","category-uncategorized"],"acf":[],"yoast_head":"\n\u00c9tude clinique : le service de r\u00e9animation poursuit ses recherches avec succ\u00e8s - Site du CHU de Poitiers<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.chu-poitiers.fr\/en\/etude-clinique-le-service-de-reanimation-poursuit-ses-recherches-avec-succes\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u00c9tude clinique : le service de r\u00e9animation poursuit ses recherches avec succ\u00e8s - Site du CHU de Poitiers\" \/>\n<meta property=\"og:description\" content=\"Le Dr Jean-Pierre Frat, praticien hospitalier en r\u00e9animation m\u00e9dicale, vient d\u2019obtenir le financement (395 000 euros) de sa future \u00e9tude via un programme hospitalier de recherche clinique (PHRC). Cette \u00e9tude, intitul\u00e9e Florali 2, va comparer deux formes d\u2019oxyg\u00e9nation avant l\u2019intubation des patients de r\u00e9animation en insuffisance respiratoire aig\u00fce : la pr\u00e9-oxyg\u00e9nation par ventilation non invasive, \u00e0 l\u2019aide d\u2019un masque recouvrant le nez et la bouche, et l\u2019oxyg\u00e9noth\u00e9rapie nasale \u00e0 haut d\u00e9bit, \u00e0 l\u2019aide de canules se pla\u00e7ant dans le nez. Sachant qu\u2019environ 25 % des patients en insuffisance respiratoire sont victimes de complication apr\u00e8s l\u2019intubation, le but est d\u2019am\u00e9liorer les conditions d\u2019oxyg\u00e9nation cinq minutes avant l\u2019intubation et de trouver la meilleure m\u00e9thode pour r\u00e9duire le risque d\u2019aggravation de l\u2019insuffisance respiratoire.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.chu-poitiers.fr\/en\/etude-clinique-le-service-de-reanimation-poursuit-ses-recherches-avec-succes\/\" \/>\n<meta property=\"og:site_name\" content=\"Site du CHU de Poitiers\" \/>\n<meta property=\"article:published_time\" content=\"2015-01-29T10:46:40+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2015-09-16T12:32:47+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.chu-poitiers.fr\/wp-content\/uploads\/2015\/01\/frat_jean_pierre_WebChu.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"762\" \/>\n\t<meta property=\"og:image:height\" content=\"800\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"ChuPoitiers\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"ChuPoitiers\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"NewsArticle\",\"@id\":\"https:\\\/\\\/www.chu-poitiers.fr\\\/en\\\/etude-clinique-le-service-de-reanimation-poursuit-ses-recherches-avec-succes\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.chu-poitiers.fr\\\/en\\\/etude-clinique-le-service-de-reanimation-poursuit-ses-recherches-avec-succes\\\/\"},\"author\":{\"name\":\"ChuPoitiers\",\"@id\":\"https:\\\/\\\/www.chu-poitiers.fr\\\/#\\\/schema\\\/person\\\/08e92cc802383a84a4efc3b8a6a6658c\"},\"headline\":\"\u00c9tude clinique : le service de r\u00e9animation poursuit ses recherches avec succ\u00e8s\",\"datePublished\":\"2015-01-29T10:46:40+00:00\",\"dateModified\":\"2015-09-16T12:32:47+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.chu-poitiers.fr\\\/en\\\/etude-clinique-le-service-de-reanimation-poursuit-ses-recherches-avec-succes\\\/\"},\"wordCount\":281,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/www.chu-poitiers.fr\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/www.chu-poitiers.fr\\\/en\\\/etude-clinique-le-service-de-reanimation-poursuit-ses-recherches-avec-succes\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.chu-poitiers.fr\\\/wp-content\\\/uploads\\\/2015\\\/01\\\/frat_jean_pierre_WebChu.jpg\",\"articleSection\":[\"Anesth\u00e9sie-r\u00e9animation\",\"Recherche\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.chu-poitiers.fr\\\/en\\\/etude-clinique-le-service-de-reanimation-poursuit-ses-recherches-avec-succes\\\/\",\"url\":\"https:\\\/\\\/www.chu-poitiers.fr\\\/en\\\/etude-clinique-le-service-de-reanimation-poursuit-ses-recherches-avec-succes\\\/\",\"name\":\"\u00c9tude clinique : le service de r\u00e9animation poursuit ses recherches avec succ\u00e8s - 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