{"id":16308,"date":"2018-04-04T17:51:02","date_gmt":"2018-04-04T15:51:02","guid":{"rendered":"https:\/\/www.chu-poitiers.fr\/?p=16308"},"modified":"2021-04-20T18:06:12","modified_gmt":"2021-04-20T16:06:12","slug":"cancerologie-digestive-pipac-une-technique-novatrice-mise-en-place-au-chu","status":"publish","type":"post","link":"https:\/\/www.chu-poitiers.fr\/en\/cancerologie-digestive-pipac-une-technique-novatrice-mise-en-place-au-chu\/","title":{"rendered":"Canc\u00e9rologie digestive\u00a0: Pipac, une technique novatrice mise en place au CHU"},"content":{"rendered":"<p>Invent\u00e9e en Allemagne, en 2011, par le Pr Marc-Andr\u00e9 Reymond, cette fa\u00e7on d\u2019administrer la chimioth\u00e9rapie s\u2019est ensuite d\u00e9velopp\u00e9e partout dans le monde. Utilis\u00e9e depuis un an et demi en France, elle a \u00e9t\u00e9 mise en place par le Dr Courvoisier au CHU l\u2019ann\u00e9e derni\u00e8re. &#8220;C\u2019est une technique novatrice car elle consiste \u00e0 administrer les produits de chimioth\u00e9rapie sous c\u0153lioscopie directement dans le ventre du patient sous forme d\u2019a\u00e9rosol sous pression, illustre le chirurgien. Une buse de n\u00e9bulisation reli\u00e9e \u00e0 un injecteur haute pression diffuse la chimioth\u00e9rapie dans tout l\u2019abdomen, puis le produit est laiss\u00e9 pendant une demi-heure dans le corps du patient avant d\u2019\u00eatre aspir\u00e9.&#8221; Ce traitement qui permet aux produits de p\u00e9n\u00e9trer en profondeur dans les tissus s\u2019intercale entre deux chimioth\u00e9rapies classiques.<\/p>\n<p>Des biopsies sont r\u00e9alis\u00e9es tout au long du traitement pour constater l\u2019\u00e9volution de la maladie. Et les premiers r\u00e9sultats sont prometteurs avec 80% d\u2019efficacit\u00e9 sur les nodules canc\u00e9reux. Les effets secondaires sont \u00e9galement moins importants que lors de l\u2019administration d\u2019une chimioth\u00e9rapie en intraveineuse.<\/p>\n<div id=\"metaslider-id-16355\" style=\"max-width: 800px; margin: 0 auto;\" class=\"ml-slider-3-113-1 metaslider metaslider-nivo metaslider-16355 ml-slider has-dots-nav ms-theme-default\" role=\"region\" aria-label=\"pipac\" data-height=\"600\" data-width=\"800\">\n    <div id=\"metaslider_container_16355\">\n        <div class='slider-wrapper theme-default'><div class='ribbon'><\/div><div id='metaslider_16355' class='nivoSlider'><img decoding=\"async\" src=\"https:\/\/www.chu-poitiers.fr\/wp-content\/uploads\/2018\/03\/IMG_0032-800x600.jpg\" height=\"600\" width=\"800\" data-caption=\"Le Dr Thomas Courvoisier, chirugien visc&eacute;ral, porte une tenue adapt&eacute;e &agrave; la technique Pipac : masque sp&eacute;cifique, gants et lunettes.\" title=\"IMG_0032\" alt=\"Le Dr Thomas Courvoisier, chirugien visc\u00e9ral, porte une tenue adapt\u00e9e \u00e0 la technique Pipac : masque sp\u00e9cifique, gants et lunettes.\" class=\"slider-16355 slide-16376 msDefaultImage\" data-no-lazy=\"1\" \/><img decoding=\"async\" src=\"https:\/\/www.chu-poitiers.fr\/wp-content\/uploads\/2018\/03\/IMG_0296.jpg\" height=\"600\" width=\"800\" data-caption=\"L&#039;&eacute;quipe chirurgicale pr&eacute;pare le mat&eacute;riel n&eacute;cessaire &agrave; une intervention avec la technique Pipac.\" title=\"IMG_0296\" alt=\"L&#039;\u00e9quipe chirurgicale pr\u00e9pare le mat\u00e9riel n\u00e9cessaire \u00e0 une intervention avec la technique Pipac.\" class=\"slider-16355 slide-16373 msDefaultImage\" data-no-lazy=\"1\" \/><img decoding=\"async\" src=\"https:\/\/www.chu-poitiers.fr\/wp-content\/uploads\/2018\/03\/IMG_0147.jpg\" height=\"600\" width=\"800\" data-caption=\"L&#039;intervention d&eacute;bute par une c&oelig;lioscopie.\" title=\"IMG_0147\" alt=\"L&#039;intervention d\u00e9bute par une c\u0153lioscopie.\" class=\"slider-16355 slide-16375 msDefaultImage\" data-no-lazy=\"1\" \/><img decoding=\"async\" src=\"https:\/\/www.chu-poitiers.fr\/wp-content\/uploads\/2018\/03\/IMG_0298.jpg\" height=\"600\" width=\"800\" title=\"IMG_0298\" alt=\"\" class=\"slider-16355 slide-16372 msDefaultImage\" data-no-lazy=\"1\" \/><img decoding=\"async\" src=\"https:\/\/www.chu-poitiers.fr\/wp-content\/uploads\/2018\/03\/IMG_0221.jpg\" height=\"600\" width=\"800\" title=\"IMG_0221\" alt=\"\" class=\"slider-16355 slide-16374 msDefaultImage\" data-no-lazy=\"1\" \/><img decoding=\"async\" src=\"https:\/\/www.chu-poitiers.fr\/wp-content\/uploads\/2018\/03\/IMG_0370-800x600.jpg\" height=\"600\" width=\"800\" data-caption=\"Une buse de n&eacute;bulisation reli&eacute;e &agrave; un injecteur haute pression diffuse la chimioth&eacute;rapie dans tout l&rsquo;abdomen, puis le produit est laiss&eacute; pendant une demi-heure dans le corps du patient avant d&rsquo;&ecirc;tre aspir&eacute;.\" title=\"IMG_0370\" alt=\"Une buse de n\u00e9bulisation reli\u00e9e \u00e0 un injecteur haute pression diffuse la chimioth\u00e9rapie dans tout l\u2019abdomen, puis le produit est laiss\u00e9 pendant une demi-heure dans le corps du patient avant d\u2019\u00eatre aspir\u00e9.\" class=\"slider-16355 slide-16368 msDefaultImage\" data-no-lazy=\"1\" \/><img decoding=\"async\" src=\"https:\/\/www.chu-poitiers.fr\/wp-content\/uploads\/2018\/03\/IMG_0304-800x600.jpg\" height=\"600\" width=\"800\" title=\"IMG_0304\" alt=\"Une buse de n\u00e9bulisation reli\u00e9e \u00e0 un injecteur haute pression diffuse la chimioth\u00e9rapie dans tout l\u2019abdomen, puis le produit est laiss\u00e9 pendant une demi-heure dans le corps du patient avant d\u2019\u00eatre aspir\u00e9.\" class=\"slider-16355 slide-16370 msDefaultImage\" data-no-lazy=\"1\" \/><img decoding=\"async\" src=\"https:\/\/www.chu-poitiers.fr\/wp-content\/uploads\/2018\/03\/IMG_0355.jpg\" height=\"600\" width=\"800\" data-caption=\"Installation finale du patient avant la vaporisation.\" title=\"IMG_0355\" alt=\"Durant une proc\u00e9dure Pipac, le patient est recouvert herm\u00e9tiquement.\" class=\"slider-16355 slide-16369 msDefaultImage\" data-no-lazy=\"1\" \/><img decoding=\"async\" src=\"https:\/\/www.chu-poitiers.fr\/wp-content\/uploads\/2018\/03\/IMG_0392.jpg\" height=\"600\" width=\"800\" data-caption=\"Un &eacute;cran permet de contr&ocirc;ler l&#039;injection des produits de chimioth&eacute;rapie.\" title=\"IMG_0392\" alt=\"Ecran permettant de contr\u00f4ler l&#039;injection des produits de chimioth\u00e9rapie.\" class=\"slider-16355 slide-16367 msDefaultImage\" data-no-lazy=\"1\" \/><\/div><\/div>\n        \n    <\/div>\n<\/div>\n<table style=\"background-color: #8d81ac;\">\n<tbody>\n<tr>\n<td>\n<p><strong>Une collaboration entre services au service du patient<\/strong><\/p>\n<p>Ce traitement novateur, de par sa sp\u00e9cificit\u00e9 et sa technicit\u00e9, a demand\u00e9 une collaboration importante entre les services de m\u00e9decine du travail, d\u2019hygi\u00e8ne et de reconstitution des chimioth\u00e9rapies, les cadres et les infirmiers de bloc op\u00e9ratoire, le cadre d\u2019anesth\u00e9sie, le cadre d\u2019hospitalisation, les m\u00e9decins anesth\u00e9sistes-r\u00e9animateurs et les chirurgiens. Le Dr Thomas Courvoisier, chirurgien visc\u00e9ral au CHU de Poitiers, a d\u00fb r\u00e9diger un protocole d\u2019utilisation propre au CHU de Poitiers en collaboration avec le Dr Soazig Rapinel, cheffe du service de m\u00e9decine du travail. Par ailleurs, le recrutement des patients pouvant b\u00e9n\u00e9ficier de cette technique se fait en partenariat avec les oncologues du CHU et lib\u00e9raux lors de r\u00e9unions pluridisciplinaires hebdomadaires.<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Le service de chirurgie visc\u00e9rale du CHU de Poitiers propose une nouvelle technique d\u2019administration de chimioth\u00e9rapie appel\u00e9e Pipac (chimioth\u00e9rapie\u2026","protected":false},"author":1,"featured_media":16363,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-16308","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Canc\u00e9rologie digestive\u00a0: Pipac, une technique novatrice mise en place au CHU - Site du CHU de Poitiers<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.chu-poitiers.fr\/cancerologie-digestive-pipac-une-technique-novatrice-mise-en-place-au-chu\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Canc\u00e9rologie digestive\u00a0: Pipac, une technique novatrice mise en place au CHU - Site du CHU de Poitiers\" \/>\n<meta property=\"og:description\" content=\"Le service de chirurgie visc\u00e9rale du CHU de Poitiers propose une nouvelle technique d\u2019administration de chimioth\u00e9rapie appel\u00e9e Pipac (chimioth\u00e9rapie intra p\u00e9riton\u00e9ale pressuris\u00e9e par a\u00e9rosols). Destin\u00e9e aux personnes atteintes de tumeurs canc\u00e9reuses du p\u00e9ritoine \u00e0 un stade avanc\u00e9, elle permet de stabiliser la maladie et d\u2019am\u00e9liorer la qualit\u00e9 de vie des patients. \u00ab Pour l\u2019instant, ce traitement est utilis\u00e9 dans un cadre palliatif, indique le Dr Thomas Courvoisier, chirurgien visc\u00e9ral au CHU de Poitiers, mais nous allons \u00e9galement participer \u00e0 une \u00e9tude nationale \u00e9valuant cette technique dans un cadre curatif.\u00a0\u00bb\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.chu-poitiers.fr\/cancerologie-digestive-pipac-une-technique-novatrice-mise-en-place-au-chu\/\" \/>\n<meta property=\"og:site_name\" content=\"Site du CHU de Poitiers\" \/>\n<meta property=\"article:published_time\" content=\"2018-04-04T15:51:02+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2021-04-20T16:06:12+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.chu-poitiers.fr\/wp-content\/uploads\/2018\/03\/IMG_0314.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"800\" \/>\n\t<meta property=\"og:image:height\" content=\"600\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"ChuPoitiers\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"ChuPoitiers\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"NewsArticle\",\"@id\":\"https:\\\/\\\/www.chu-poitiers.fr\\\/cancerologie-digestive-pipac-une-technique-novatrice-mise-en-place-au-chu\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.chu-poitiers.fr\\\/cancerologie-digestive-pipac-une-technique-novatrice-mise-en-place-au-chu\\\/\"},\"author\":{\"name\":\"ChuPoitiers\",\"@id\":\"https:\\\/\\\/www.chu-poitiers.fr\\\/#\\\/schema\\\/person\\\/08e92cc802383a84a4efc3b8a6a6658c\"},\"headline\":\"Canc\u00e9rologie digestive\u00a0: Pipac, une technique novatrice mise en place au CHU\",\"datePublished\":\"2018-04-04T15:51:02+00:00\",\"dateModified\":\"2021-04-20T16:06:12+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.chu-poitiers.fr\\\/cancerologie-digestive-pipac-une-technique-novatrice-mise-en-place-au-chu\\\/\"},\"wordCount\":349,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/www.chu-poitiers.fr\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/www.chu-poitiers.fr\\\/cancerologie-digestive-pipac-une-technique-novatrice-mise-en-place-au-chu\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.chu-poitiers.fr\\\/wp-content\\\/uploads\\\/2018\\\/03\\\/IMG_0314.jpg\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.chu-poitiers.fr\\\/cancerologie-digestive-pipac-une-technique-novatrice-mise-en-place-au-chu\\\/\",\"url\":\"https:\\\/\\\/www.chu-poitiers.fr\\\/cancerologie-digestive-pipac-une-technique-novatrice-mise-en-place-au-chu\\\/\",\"name\":\"Canc\u00e9rologie digestive\u00a0: Pipac, une technique novatrice mise en place au CHU - 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